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A post-emergence herbicide for use on winter and spring wheat, winter and spring barley, winter and spring oats and winter rye and triticale.

A suspo-emulsion formulation containing 2.5 g/l (0.25% w/w) florasulam and 100 g/l (10% w/w) fluroxypyr (present as 144 g/l fluroxpyr-meptyl). Contains 1,2-benzisothiazol-3(2H)-one. May produce an allergic skin reaction

DIRECTIONS FOR USE
IMPORTANT: This information is approved as part of the Product Label. All instructions within this section must be read carefully in order to obtain safe and successful use of this product.

GENERAL INFORMATION
CLEAVE® is a contact herbicide which is mainly absorbed by the leaves. The optimum timing is to apply CLEAVE when the weeds are small and actively growing.

RESTRICTIONS OR WARNINGS
DO NOT apply when crop is under stress, such as in frosty weather or when frost is expected, insect attack, manganese deficiency, wind damage or where there is possible check from earlier pesticide treatments. DO NOT overlap spray swaths. Extreme care must be taken to avoid spray drift onto non-crop plants outside of the target area. Applications of CLEAVE may cause transient symptoms of phytotoxicity.

RESISTANCE
CLEAVE contains two active ingredients with different modes of action and therefore the risk of resistance building up is reduced. CLEAVE contains florasulam which acts by inhibition of actolactate synthase (ALS) and is classified as a group B-Herbicide by the Herbicide Resistance Action Committee (HRAC) and fluroxypyr-meptyl classified as a synthetic auxin and acts like indoleacetic acid within the plants. The Herbicide Resistance Action Committee (HRAC) grouped this mode of action in the international HRAC group O (Synthetic Auxins). Repeated use of herbicides with the same mode of action can increase the risk of strains of weeds developing resistance to these compounds, leading to poor control. In order to minimise the risk, a strategy for preventing and managing such resistance should be adopted. Growers are advised to apply products containing herbicides with different modes of action in sequence or tank-mix where two or more components are active against the target weeds. Use the recommended rate of CLEAVE and the correct application timing for the hardest to control weed species present in the field. The above should be used in conjunction with effective cropping rotation and cultivation techniques e.g. stale seedbed, cultivation and use of non-selective herbicide prior to drilling. Further guidance on weed resistance management is available from the Herbicide Resistance Action Committee (HRAC) and Weed Resistance Action Group (WRAG). Follow WRAG Guidelines.

CROP SPECIFIC INFORMATION
CLEAVE may be applied to all varieties of winter and spring wheat, barley, oats and winter rye and triticale.
Winter wheat, barley, rye and triticale
Apply in the spring from the 3 leaf stage of the crop (GS 13) and up to and including late boot stage-flag leaf sheath swollen stage (BBCH GS 45).
Spring wheat and barley
Apply in the spring from the 3 leaf stage of the crop (GS 13) and up to and including flag leaf ligule just visible (BBCH GS 39).
Winter and spring oats
Apply in the spring from the 3 leaf stage of the crop (GS 13) and up to and including first node detectable. (BBCH GS 31).

RATE OF USE AND WATER VOLUME
Apply CLEAVE at 1.0-1.5 L/ha in 200-300 litres water per hectare as a MEDIUM spray (BCPC category). The lower rate of CLEAVE should only be used on susceptible weed species that are small and actively growing at the time of application. For more details see weed susceptibility table above. Qualified recommendation: lower water volumes of 100 L/ha may also be used, however these have not been supported by effectiveness or crop safety data. As CLEAVE has contact activity, it is important to achieve a good coverage of the crop when spraying.

FOLLOWING CROPS
Cereals, maize, sugar beet, oilseed rape, grass, carrots, sunflowers and peas may be sown in the calendar year following treatment with CLEAVE. There is no need to plough before drilling the following crop. In the event of crop failure for any reason these crops may also be sown, although vigour reductions in following crops of oilseed rape may be seen after a dry summer. This will be outgrown and will not result in yield loss.

MIXING AND SPRAYING
For use by tractor mounted/trailed sprayer only. Ensure the sprayer is clean and in good working order. Calibrate according to the sprayer manufacturer’s recommendations. Half-fill the spray tank with clean water and begin agitation. Add the required quantity of CLEAVE to the tank and complete filling. Continue agitation until spraying is complete. On emptying the container, RINSE CONTAINER THOROUGHLY by using an integrated pressure rinsing device or manually rinsing three times. Add washings to sprayer at time of filling and dispose of container safely. Do not leave the sprayer standing with the spray mixture in it for a long period of time.

TANK-MIXTURES
Where tank-mixes are used, and unless directed otherwise, the preferred order of addition of products to the spray tank is as follows: water dispersible granules, wettable powders, suspension concentrates (flowables), emulsifiable concentrates, solution concentrates. Each product should be added to the half-full sprayer and be fully dispersed before the addition of the next product.

COMPATIBILITY AND SEQUENCES
CLEAVE must not be used in mixture or in sequence with any other product containing an ALS inhibitor.

Joint application
A joint application refers to use of one product in tank-mixture or sequence with a second product. CLEAVE can be applied to a cereal crop in joint application with one of the following alternative ALS inhibitor products (in the Republic of Ireland only products marked with a #). Only one other ALSinhibitor product can be applied to a cereal crop also treated with CLEAVE. In addition, the maximum total dose of florasulam (see ‘other specific restrictions’), taking into consideration the contributions from both applied products, must not be exceeded. Where the product is marked* the product may be applied in a joint application with CLEAVE either as a convenience tank-mix partner or in sequence. Otherwise, the joint application with CLEAVE can only be made in sequence and not in tank-mix