Proline 275Plant Protection Product ComparisonPlant Protection Product ComparisonReport inaccuraciesReport inaccuracies

A triazolinthione fungicide for the control of stem-base, foliar and ear disease in winter and spring wheat (also reduction of the mycotoxin deoxynivalenol), Durum wheat, winter rye, winter and spring barley, winter and spring oats and for disease control in winter oilseed rape.

USE ONLY AS AN AGRICULTURAL FUNGICIDE
WINTER and SPRING WHEAT, DURUM WHEAT
Maximum individual dose: 0.72 L product/ha
Maximum total dose: 2.16 L product/ha
Latest time of application: before grain milky ripe stage

WINTER RYE, WINTER and SPRING BARLEY, WINTER and SPRING OATS
Maximum individual dose: 0.72 L product/ha
Maximum total dose: 1.44 L product/ha
Latest time of application: Up to beginning of flowering

WINTER OILSEED RAPE
Maximum individual dose: 0.63 L product/ha
Maximum total dose: 1.26 L product/ha
Latest time of application: 56 days before harvest

DIRECTIONS FOR USE
IMPORTANT: This information is approved as part of the Product Label. All instructions within this section must be read carefully in order to obtain safe and successful use of this product.

DISEASES CONTROLLED
Wheat
Eyespot, Septoria (leaf and glume blotch), powdery mildew, yellow rust, brown rust*, tan spot*, ear disease complex – Fusarium ear blight* (reduction of deoxynivalenol) and reduction of sooty moulds.

Barley
Eyespot, powdery mildew, yellow rust, brown rust, ear disease complex – Fusarium ear blight* and reduction of sooty moulds, Rhynchosporium and net blotch.

Rye
Eyespot, powdery mildew, brown rust and Rhynchosporium.

Oats
Eyespot, crown rust and mildew

Winter oilseed rape
Light leaf spot*, Phoma leaf spot and stem canker and Sclerotinia stem rot.
*Proline 275 will provide moderate control of these diseases

CEREALS
Eyespot (Tapesia spp.) Spray in the spring at the first sign of disease, from when the leaf sheaths begin to become erect until the 2nd node is detectable (GS 30-32).

Septoria Leaf Blotch and Glume Blotch (Septoria tritici and Stagonospora nodorum)
Apply before disease is established in the crop. To protect the upper leaves and ear apply Proline 275 at full flag leaf emergence (GS 37) up to mid-flowering (GS 65). Where disease pressure remains high application may be repeated. Applications to upper leaves where S. tritici symptoms are present are likely to be less effective.
Proline 275 contains a DMI fungicide. Resistance to some DMI fungicides has been identified in Septoria leaf blotch (Mycosphaerella graminicola) which may seriously affect the performance of some products. For further advice on resistance management in DMI’s contact your agronomist or specialist advisor, and visit the FRAG-UK website.

Powdery Mildew (Blumaria graminis)
Apply Proline 275 at the first signs of disease. Where disease pressure remains high application may be repeated.

Yellow Rust (Puccinia striiformis)
Apply Proline 275 at the first signs of disease. Proline 275 controls yellow rust in wheat and winter barley. A second application may be made 2-3 weeks later if re-infection occurs. Applications made
to established infections are likely to be less effective.

Brown Rust
Apply Proline 275 at the first signs of disease. Proline 275 controls brown rust in barley (Puccinia hordei) and rye (P. recondita) and will give moderate control of brown rust in wheat (P. recondita). A
second application may be made 2-3 weeks later if re-infection occurs. Applications made to established infections are likely to be less effective.

Crown Rust (Puccinia coronata)
Apply Proline 275 at the first signs of disease. Proline 275 controls crown rust in winter and spring oats. A second application may be made 2-3 weeks later if re-infection occurs. Applications made to
established infections are likely to be less effective.

Tan Spot (Pyrenophora tritici-repentis)
Apply Proline 275 at the first signs of disease in spring/early summer. Proline 275 will give moderate control of tan spot in winter wheat. Where disease pressure remains high application may be repeated.

Ear Disease Complex
Apply Proline 275 soon after ear emergence until the end of flowering (GS59-69) for moderate control of Fusarium ear blight and reduction of sooty moulds. Control of ear diseases can result in cleaner, brighter ears. Through the reduction of ear blight, Proline 275 effectively reduces the level of the Fusarium mycotoxin deoxynivalenol (DON) in wheat grain. However, where Fusarium levels are high, the reduction achieved may not always be sufficient to ensure that DON levels fall below the statutory limit.

Leaf Blotch (Rhynchosporium secalis)
Proline 275 gives high levels of Rhynchosporium control. Apply Proline 275 in spring at the first signs of disease. For severe infections a second application may be necessary 2-3 weeks later.

Net Blotch (Pyrenophora teres)
Apply Proline 275 at the first signs of disease in spring/early summer. For severe infections, a second application 2-3 weeks later will give most effective control when conditions remain favourable for disease development.

WINTER OILSEED RAPE
Light Leaf Spot
Apply Proline 275 in autumn/winter (usually late October to early December) protectively. Follow up spray(s) may be required in early spring from the onset of stem elongation, depending on disease
development.

Phoma Leaf spot/Stem Canker
Apply Proline 275 in autumn at the first sign of disease. Repeat application in late autumn/winter, if disease symptoms reoccur.

Sclerotinia stem rot (Sclerotinia sclerotiorum)
Apply Proline 275 at early to full flower.
Spring oilseed rape (QUALIFIED MINOR USE RECOMMENDATION) Proline 275 can also be used on varieties of spring oilseed rape but crop safety has not been fully established.

RESISTANCE
Repeated application of Proline 275 alone should not be used on the same crop against a high risk pathogen such as cereal powdery mildew. Tank-mixtures or alternation with fungicides having a different mode of action (e.g. morpholines) have been shown to protect against the development of resistant forms of disease. The possible development of disease strains resistant to Proline 275 cannot be excluded or predicted. Where such resistant strains occur, Proline 275 is unlikely to give satisfactory control.
Strains of light leaf spot resistant to azole fungicides are known to exist. To avoid development of resistance apply product protectively in response to disease forecasts. Where possible, when light leaf spot is present, avoid the use of azole based fungicides when targeting other diseases such as Sclerotinia at mid flowering stage.

CROP SPECIFIC INFORMATION
Cereals
Apply Proline 275 at 0.72 L/ha in 100-300 L water/ha.
Apply as a MEDIUM spray quality (as defined by BCPC). A spray pressure of 2-3 bar is recommended. Maximum total dose per crop is 1.44 L/ha for barley and oats and 2.16 L/ha for wheat and rye. Proline 275 may be applied at any stage before grain milky ripe stage (GS71) in winter wheat and winter rye and up to beginning of flowering in barley and oats.

Winter Oilseed Rape
Apply Proline 275 at 0.63 L/ha in 100-300 L water/ha.
Apply as a MEDIUM spray quality (as defined by BCPC). A spray pressure of 2-3 bar is recommended. Maximum total dose per crop is 1.26 L/ha. Proline 275 may be applied at anystage up to a pre harvest interval of 56 days.
Apply Proline 275 in 100 to 300 litres of water per hectare. The higher spray volumes are recommended where the crop is dense or disease pressure / risk is high to ensure good penetration to the lower leaves and stem bases. Disease control may be compromised by reducing water volumes, where good spray coverage is difficult to achieve.

MIXING AND SPRAYING
Thoroughly shake the pack before use. Add the required quantity of Proline 275 to the half-filled spray tank with the agitation system in operation and then fill to the required level. Continue agitation at all times during spraying and stoppages until the tank is completely empty. Spray immediately after mixing. Sprayers should be thoroughly cleaned before use, and filters and jets checked for damage and blockages. Boom height should be adjusted to ensure even coverage of the crop, particularly at later growth stages. The correct height is one at which the spray from alternate nozzles meets just above the crop. In dense crops, at later growth stages, higher water volumes should be used. Spray equipment should be thoroughly cleaned with detergent after use.