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DIRECTIONS FOR USE
IMPORTANT: This information is approved as part of the Product Label. All instructions within this section must be read carefully in order to obtain safe and successful use of this product.
TOLEDO is recommended for control of a wide range of diseases on winter and spring sown cereals, oilseed rape and field beans, cabbages, carrots, horseradish, leeks, linseed, parsnips, swedes and turnips.
For best disease control and yield benefit TOLEDO should be applied at an early stage of disease development, before infection spreads to new crop growth.

RESISTANCE MANAGEMENT
TOLEDO contains a triazole fungicide that belongs to the group of DeMethylation Inhibitors (DMI). Repeated applications of DMI products may result or may already have resulted into the occurrence of less sensitive pathogens to DMI fungicides.
Therefore, repeated application of TOLEDO alone should not be used on the same crop against a high risk pathogen such as cereal powdery mildew and Septoria leaf blotch. It is important to use the recommended rate. Tank mixtures or alternation with fungicides having a different mode of action (e.g. morpholines) have been shown to protect against the development of resistant forms of disease. When used in tank mixture, the recommended TOLEDO rate should be maintained. The possible development of diseases resistant to TOLEDO cannot be excluded or predicted. Where such resistant strains occur, TOLEDO is unlikely to give satisfactory control.
Resistance to some DMI fungicides has been identified in Septoria leaf blotch (Septoria tritici) which may seriously affect the performance of some products. For further advice on resistance management in DMI's contact your agronomist or specialist advisor and visit the Fungicide Resistance Action Group (FRAG)-UK website.

DISEASES
Cereals:
Wheat: Septoria Leaf Spot (Septoria tritici), Glume Blotch (Septoria nodorum), Ear disease complex (incl. Fusarium spp, Alternaria and Cladosporium), Yellow Rust (Puccinia striiformis), Brown Rust (Puccinia recondita), and Powdery Mildew (Erysiphe graminis).
Triticale: Septoria Leaf Spot (Septoria tritici), Glume Blotch (Septoria nodorum), Yellow Rust (Puccinia striiformis), Brown Rust (Puccinia recondita), Powdery Mildew (Erysiphe graminis), and Fusarium ear disease (Fusarium spp,).
Barley: Yellow Rust (Puccinia striiformis), Brown Rust (Puccinia hordei), Powdery Mildew (Erysiphe graminis), Leaf Blotch (Rhynchosporium secalis), and Net Blotch (Helminthosporium teres).
Rye: Yellow Rust (Puccinia striiformis), Brown Rust (Puccinia recondita), Powdery Mildew (Erysiphe graminis), and Leaf Blotch (Rhynchosporium secalis).
Oats: Crown Rust (Puccinia coronata)
Swedes & Turnips: Powdery Mildew (Erysiphe cruciferarum)
Oilseed rape: Light Leaf Spot (Pyrenopeziza brassicae), Phoma Leaf Spot / Stem Canker (Leptosphaeria maculans), Dark Leaf Spot/Pod Spot (Alternaria brassicae), Sclerotinia Stem Rot (Sclerotinia sclerotiorum), Ringspot (Mycosphaerella brassicicola). Plant growth regulating effect.
Leeks: Rust (Puccinia allii)
Cabbage: Black spot (Alternaria spp.), Light Leaf Spot (Pyrenopeziza brassicae), Powdery Mildew (Erysiphe cruciferarum), Ringspot (Mycosphaerella brassicicola).
Linseed: Powdery Mildew (Oidium lini), Grey mould (Botrytis cinerea)ans: Chocolate Spot (Botrytis fabae), Bean rust (Uromyces viciafabae)
Field Beans: Chocolate Spot (Botrytis fabae), Bean rust (Uromyces viciafabae)
Carrots: Blight (Alternaria dauci), Powdery Mildew (Erysiphe heraclei), Sclerotinia (Sclerotinia sclerotiorum)
Horseradish: Black spot (Alternaria spp.) Parsnips: Powdery mildew (Erysiphe spp.)

APPLICATION
Rate of use Dose: 0.6 liters per hectare on all named crops
Sprayers should be THOROUGHLY CLEANED before use and filters and jets checked for damage and blockages.
A pressure of 2-3 bar (30-40 psi) is recommended.
Apply as a MEDIUM quality spray (as defined by BCPC).
Boom height and water volume should be adjusted to ensure good coverage of the crop, particularly at later growth stages. In dense crops at later growth stages, higher water volumes should be used as recommended.

CROP SPECIFIC INFORMATION
TOLEDO may be used on all varieties of winter and spring sown wheat (excluding durum wheat), barley, triticale and rye, but ONLY on the following varieties of winter and spring oats:
Winter oat varieties which may be treated with TOLEDO. Aintree, Chamois, Craig, Emperor, Gerald, Kynon, Mirabel, Pennal, Solva
Spring oat varieties which may be treated with TOLEDO Aberglen, Cabana, Commander, Dula, Melys, Minerva, Rhiannon, Ripon

Dose: 0.6 litre per hectare.
Maximum 2 applications per crop Water Volume Most crops 100-200 litres/hectare Dense crops after the first node is detectable up to 250 litres/hectare Large crops, varieties highly susceptible to disease up to 300 litres/hectare

Wheat: TOLEDO may be applied at any stage before end of flowering (GS 69).
Triticale, barley, rye, and oats: TOLEDO may be applied at any stage before beginning of flowering (GS 61).

Diseases Controlled - Application Timing
Septoria Leaf Spot (Septoria tritici) and Glume Blotch (Septoria nodorum) (Wheat, triticale) To protect the flag leaf and ear from Septoria tritici and Septoria nodorum apply TOLEDO from beginning of stem elongation (GS 30) until beginning of flowering (GS 61). Repeated application may be necessary where there is a high risk of Septoria tritici - see “Resistance management”. TOLEDO should be applied when the disease is active, but before it is visible on the upper leaves. Applications made once foliar symptoms of S. tritici are already present on the upper leaves will be less effective since these symptoms only develop several weeks after initial crop infection has taken place.
Yellow Rust (Puccinia striiformis) and Brown Rust (Puccinia recondita) (Wheat, triticale, barley and rye) Apply TOLEDO at the first signs of disease. Applications made to established infections are likely to be less effective. A second application may be made 2-3 weeks later if reinfection occurs.
Crown Rust (Puccinia coronata) (Oats) Apply TOLEDO on first appearance of crown rust.
Ear Disease Complex (Wheat) TOLEDO applied soon after ear emergence can give a good reduction of Fusarium ear blight and a reduction of sooty moulds (Alternaria and Cladosporium) and can result in cleaner, brighter ears. TOLEDO applied between early flowering – end of flowering (GS 61-69) gives a good control of Fusarium ear blight. Apply TOLEDO when conditions for Fusarium infection are favourable.
Fusarium Ear Disease (Triticale) TOLEDO applied soon after ear emergence can give a good reduction of Fusarium ear blight. TOLEDO applied between early flowering – end of flowering (GS 61-69) gives a good control of Fusarium ear blight. Apply TOLEDO when conditions for Fusarium infection are favourable.
Powdery Mildew (Erysiphe graminis) (Wheat, triticale, barley and rye) For a moderate control of powdery mildew. TOLEDO should be applied at first signs of disease. When treating established mildew or particularly disease susceptible varieties, improved control can be achieved by adding a half dose of an approved fenpropimorph formulation. When disease pressure remains high application may be repeated if necessary - see “Resistance management”
Leaf blotch (Rhynchosporium secalis) (Barley, rye) For a moderate control of leaf blotch. Apply TOLEDO at the onset of disease. For effective control of moderate to severe infections a second application may be necessary 2-3 weeks later. On disease susceptible varieties in high risk situations tank mixing TOLEDO with other products may improve control. See recommendations made under 'Resistance Management'.
Net blotch (Pyrenophora teres) (Barley) For some control of net blotch. Apply TOLEDO at the very first signs of disease in spring/early summer. A second application 2-3 weeks later will give most effective control when conditions remain favourable for disease development. See recommendations made under 'Resistance Management'. When disease develops after flag leaf emergence a single application of TOLEDO will generally provide good protection.

FACTORS AFFECTING CROP SAFETY
Occasionally, after the application of TOLEDO, some transient leaf speckling on wheat or leaf reddening/scorch on oats may occur, but these symptoms have not been shown to adversely affect yield responses accruing from the benefits of disease control.

OILSEED RAPE
TOLEDO may be used on all varieties of winter or spring sown oilseed rape. Dose: 0.6 litre per hectare. Maximum 2 applications per crop TOLEDO should be applied in 100-400 L/ha of water, using the higher volume in dense crops. TOLEDO may be applied at any time up to and including full flowering (GS 69) or not less than 56 days before harvest.

Diseases Controlled
Phoma Leaf Spot/Stem Canker (Leptosphaeria maculans) Leaf spot can be found from October onwards and best control of stem canker may be expected from an autumn application (GS 14-18) applied at first signs of disease, followed by an application late winter/early spring (GS 39-65). TOLEDO programmes applied against light leaf spot will also give a good reduction of leaf spot/stem canker.
Light Leaf Spot (Pyrenopeziza brassicae) Light leaf spot can be found in early spring / summer. Apply TOLEDO as from onset of stem extension at 0.6 L/ha.
Dark Leaf/Pod Spot (Alternaria spp) Treatment with 0.6 L/ha TOLEDO should begin at the onset of disease i.e. when black pinhead spots first appear on the pods. Apply TOLEDO around full flowering (GS 65).
Sclerotinia Stem Rot 0.6 L/ha TOLEDO applied at early to full flowering (GS61-65) will give some reduction of Sclerotinia stem rot.
Ringspot (Mycosphaerella brassicicola) Spring/summer applications of TOLEDO at crop stage 9 or more extended internodes to first petals visible (GS 39-55) may also give some reduction of this disease.
Plant Growth Regulation. To protect oilseed rape plants from crop damage in periods of low temperatures and frost during winter, apply TOLEDO as from 4-leaf stage to 8 leaf stage (GS 14-18) in autumn at 0.6 L/ha. Application should be made only in those crops with a risk of excessive crop growth in late autumn. The growth regulating effect is dependent on crop growing conditions and oilseed rape vDiseases Controlled - Application Timing Chocolate Spot (Botrytis fabae) and Bean Rust (Uromyces fabae) TOLEDO should be applied at first signs of disease as from the early flower stage (GS 61), and repeated 3-4 weeks later (individual beans visible inside pods (GS 79), will give good control of both diseases.ariety.
To improve on crop stability and decrease risk of premature lodging of oilseed rape, apply TOLEDO in autumn (GS 14-18) and early spring (GS 30-39), both at 0.6 L/ha. Application should only be made on vigorously growing crops with a risk to lodging.

FIELD BEANS
Dose: 0.6 litre per hectare. Maximum 2 applications per crop TOLEDO should be applied in 200-600 L/ha of water, using the higher volume in dense crops. TOLEDO must not be applied less than 35 days before harvest.

Diseases Controlled - Application Timing
Chocolate Spot (Botrytis fabae) and Bean Rust (Uromyces fabae) TOLEDO should be applied at first signs of disease as from the early flower stage (GS 61), and repeated 3-4 weeks later (individual beans visible inside pods (GS 79), will give good control of both diseases.

CABBAGES
Dose: 0.6 litre per hectare. Maximum 3 applications per crop TOLEDO should be applied in 200-600 L/ha of water, using the higher volume in dense crops. TOLEDO must not be applied less than 21 days before harvest. Consult processor before using TOLEDO.

Diseases Controlled - Application Timing
Black spot (Alternaria spp), Light Leaf Spot (Pyrenopeziza brassicae), Powdery Mildew (Erysiphe cruciferarum) & Ringspot (Mycosphaerella brassicicola). A programme of 3 sprays of TOLEDO at 0.3 L/ha at 21-28 day intervals will give good control of all four diseases. Best results will be obtained when spraying begins at first signs of disease, but TOLEDO should not be applied before the beginning of cabbage heart formation.
Where Ringspot has become established the first spray may be applied at up to 0.6 litre/ha and can improve activity; subsequent applications may be required to maintain control but the maximum total dose of 1.8 L/ha per crop must not be exceeded.

CARROTS, PARSNIPS AND HORSERADISH
Dose: 0.6 litre per hectare. Maximum 3 applications per crop Apply in 200-600 litres of water/ha. Good cover of the foliage is vital; use the higher volume in dense or well grown crops. TOLEDO must not be applied less than 21 days before harvest.

Diseases Controlled - Application Timing
Alternaria spp (Carrots and horseradish) To reduce Alternaria infection on the leaves begin a programme of TOLEDO sprays with an application in early/mid-August, or when first signs of disease appear on the foliage always after crop stage GS 40. Up to 2 further applications may be made at 3-week intervals.
Powdery Mildew (Carrots, parsnips) TOLEDO gives a useful reduction of powdery mildew if applied when the disease is first seen in the crop, but applied after crop stage GS 40. Up to two follow-up applications may be made if necessary, at 14-21 day intervals.
Sclerotinia (Carrots) A programme of TOLEDO sprays applied against Alternaria spp can also provide a useful reduction in Sclerotinia infection.

SWEDES AND TURNIPS
Dose: 0.6 litre per hectare. Maximum 2 applications per crop TOLEDO should be applied in 200-600 L/ha of water, using the higher volume in dense crops. TOLEDO must not be applied less than 35 days before harvest. Consult processor before using TOLEDO.

Diseases Controlled - Application Timing
Powdery Mildew (Erysiphe cruciferarum) Application of TOLEDO at first signs of disease will give good control. However, do not apply TOLEDO before a root diameter of 2.5 cm has been reached. In situations of very early disease development and extended infection pressure, a second application may be necessary.

LINSEED
Dose: 0.6 litre per hectare. Maximum 2 applications per crop TOLEDO should be applied in 100-400 L/ha of water, using the higher volume in dense crops. TOLEDO may be applied at any time before brown capsule stage or 35 days before harvest whichever is sooner

Diseases Controlled - Application Timing
Powdery Mildew (Oidium lini) : TOLEDO applied at first signs of disease will give control. Grey mould (Botrytis cinerea): TOLEDO applied at first signs of disease can give a reduction in this disease.

LEEKS
Dose: 0.6 litre per hectare. Maximum 3 applications per crop TOLEDO should be applied in 400-600 L/ha of water, using the higher volume in dense crops. TOLEDO must not be applied less than 21 days before harvest.

Diseases Controlled - Application Timing
Rust (Puccinia allii) Apply TOLEDO at 0.6 L/ha at first signs of disease; this usually occurs during warm, humid weather from August onwards. Up to 2 further applications at 14- 21 day intervals may be made if weather conditions favour disease development.

COMPATIBILITY
TOLEDO may be applied as a tank-mix with a range of products. Contact Rotam Europe Ltd or distributor for compatibility information on specific tankmixes. Requirements and restrictions on all tank-mixed products labels must be adhered to when using in tank mixture.

MIXING
Thoroughly shake the pack before use. Add the required quantity of TOLEDO to the half-filled spray tank with the agitation system in operation and then fill to the required level. Continue agitation at all times during spraying and stoppages until the tank is completely empty. Spray immediately after mixing. Where tank mixes are used TOLEDO should be added to the spray tank last, after first dispersing the other product(s), unless otherwise specified. On emptying the container, RINSE CONTAINER THROUGHLY by using an integrated pressure rinsing device or manually rinsing three times. Add washing to sprayer at time of filling and dispose of container safely.

HARVEST INTERVAL
Before grain milky rape stage or 35 days before harvest for wheat, barley, triticale, rye and oats. Before most seeds are green – brown mottled or 56 days before harvest.for oilseed rape. Not less than 21 days before harvest for cabbages, carrots, leeks, parsnips and horseradish; Not less than 35 days before harvest for field beans, swedes and turnips; At any time before brown capsule stage or 35 days before harvest whichever is sooner for linseed.