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FirstStep Herbicide Tank Mix must be applied to emerged, actively growing weeds. Warm, moist growing conditions promote active weed growth and enhance the activity of FirstStep Herbicide Tank Mix by allowing maximum foliar uptake and contact activity. Weeds hardened off by cold weather or drought stress may not be adequately controlled or suppressed and re-growth may occur. For best results, ensure thorough spray coverage of target weeds. FirstStep Herbicide Tank Mix rapidly stops growth of susceptible weeds.

However, typical symptoms (discoloration) of dying weeds may not be noticeable for one to two weeks after application depending upon growing conditions and weed susceptibility. Degree of control and duration of effect are dependent upon weed species, sensitivity, weed size, crop competition, growing conditions immediately prior to and following treatment, and spray coverage. Delay application until weeds have emerged to the stages described to provide adequate leaf surface to receive the herbicide. Unemerged weed seedlings or vegetation arising from underground rhizomes or root stocks of perennials will not be affected by the herbicide. For this reason, best control of most perennial weeds is obtained when treatment is made at late growth stages approaching maturity.