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For preplant and preemergence weed control in field corn and for preplant weed control in cotton, peanuts and soybeans

LEADOFF herbicide is a water soluble granule containing 33.4% active ingredient by weight. LEADOFF  is a selective herbicide for burndown and residual control of certain annual grass and broadleaf weeds when applied preplant or preemergence to field corn. It may also be applied 30 days or more preplant to cotton or soybeans and 45 days or more preplant to peanuts for winter vegetation management. Residual weed control is dependent on rainfall or sprinkler irrigation for herbicide activation. LEADOFF herbicide may be applied in tank mixtures with other herbicides labeled for use in the intended crop. However, in the case of tank mixes with other herbicides, the most restrictive label must be followed.
LEADOFF is absorbed through the roots and leaf tissue of plants, rapidly inhibiting the growth of susceptible weeds. Rainfall or sprinkler irrigation is needed to move LEADOFF into the soil. Susceptible weeds will generally not emerge from preemergence application. In some cases susceptible weeds may germinate and emerge a few days after application, but growth then ceases and leaves become chlorotic three to five days after emergence. Death of leaf tissue and growing point will follow in some species, while others will remain green but stunted and noncompetitive The herbicidal action of DuPont LEADOFF may be less effective on weeds stressed from adverse environmental conditions (such as extreme temperatures or moisture), abnormal soil conditions, or cultural practices.

Do not plant cotton or soybeans less than 30 days following an application of 1.5 ounces per acre of LEADOFF herbicide or less than 60 days following an application of >1.5 to 2.0 ounces per acre of LEADOFF.
Do not plant field corn less than 30 days following an application of LEADOFF in the states of Florida east of US 231 and Georgia.
Do not plant peanuts less than 45 days following an application of LEADOFF.
Do not apply the organophosphate insecticide "Counter" within 30 days of a preplant or preemerge application of LEADOFF except in the sates of Alabama, Florida and Georgia in which case do not apply the organophosphate insecticide "Counter" within 45 days of a preplant or preemerge application of LEADOFF since crop injury may result.
Do not apply more than a total of 1.0 oz active ingredient rimsulfuron per acre per crop year to field corn or soybeans from all sources. In field corn this includes combinations of preplant and preemergence applications of DuPont INSTIGATE, LEADOFF and DuPont PREQUEL, as well as rimsulfuron from postemergence application(s) of products such as DuPont REALM Q, DuPont STEADFAST Q or DuPont RESOLVE Q. In soybeans this includes the preplant application of LEADOFF.
Do not apply more than a total of 0.5 oz active ingredient rimsulfuron per acre per crop year to cotton or peanuts from all sources. This includes the preplant application of LEADOFF.
Do not apply to coarse textured soils (sand, loamy sand or sandy loam) with less than 1% organic matter.
Do not apply during a temperature inversion, when winds are gusty, or when conditions favor poor coverage and/or off target spray movement.
Do not apply postemergence to any crop.
Do not make more than 1 application of LEADOFF per use season.
The maximum use rate for corn is 2.7 ounces of LEADOFF per acre. The maximum preplant use rate for cotton or soybeans is 2 ounces per acre. The maximum preplant use rate for peanuts is 1.5 ounces per acre.
Do not graze, feed forage, grain or fodder (stover) from treated areas to livestock within 30 days of LEADOFF application.
Injury or loss of desirable trees or vegetation may result from failure to observe the following:
- Do not apply LEADOFF or drain or flush application equipment on or near desirable trees or other plants, or on areas where their roots may extend, or in locations where the chemical may be washed or moved into contact with their roots.
- Do not use on lawns, walks, driveways, tennis courts, or similar areas.
- Do not contaminate any body of water.

Allow at least 3 weeks between preemergence applications of LEADOFF and postemergence applications of rimsulfuron containing products, such as REALM Q, STEADFAST Q, or RESOLVE Q. LEADOFF may interact with certain insecticides applied to soybean, peanuts, cotton, or corn. Crop response varies with field crop, insecticide used, insecticide application method, and soil type. LEADOFF may be applied to crops previously treated with “Fortress”, “Aztec”, or “Force” insecticides or other nonorganophosphate (OP) soil insecticides regardless of soil type. Preplant/Preemergence applications of LEADOFF to corn where an application of “Lorsban", or “Thimet” is planned may cause unacceptable crop injury, especially on soils of less than 4% organic matter. Crop injury may occur following an application of LEADOFF if there is a prolonged period of cold weather and/or in conjunction with wet soils.
Bedding flat ground or rebuilding beds in fields treated with LEADOFF may increase the potential of crop response due to an increased concentration of herbicide in the planting-seed zone. Prevent drift or spray to desirable plants. Thoroughly clean application equipment immediately after use. It is recommended to flush the sprayer system and recharge with clean water when there are extended periods between LEADOFF applications. See Sprayer Cleanup section of this label for instructions.

LEADOFF, which contains the active ingredients rimsulfuron and thifensulfuron -methyl, is a Group 2 herbicide based on the mode of action classification system of the Weed Science Society of America. When herbicides with mode of action classifications that affect the same biological sites of action are used repeatedly over several years to control the same weed species in the same treatment area, naturally-occurring resistant biotypes may survive a correctly applied herbicide treatment, propagate, and become dominant in that area. Adequate control of these resistant weed biotypes cannot be expected. If weed control is unsatisfactory, it may be necessary to retreat the problem area using a product affecting a different biological site of action. To better manage herbicide resistance through delaying the proliferation and possible dominance of herbicide resistant weed biotypes, it may be necessary to change cultural practices within and between crop seasons such as using a combination of tillage, retreatment, tank-mix partners and/or sequential herbicide applications that affect a different site of action. Weed escapes that are allowed to go to seed, and movement of plant material between treatment areas on equipment will promote the spread of resistant biotypes. It is advisable to keep accurate records of pesticides applied to individual fields to help obtain information on the spread and dispersal of resistant biotypes. Consult your agricultural dealer, consultant, applicator, and/or appropriate state agricultural extension service representative for specific alternative cultural practices or herbicide recommendations available in your area.

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